Amy F.T. Arnsten Ph.D.

  • Albert E. Kent Professor of Neuroscience and Professor of Psychology
  • Member, Kavli Institute of Neuroscience at Yale University

Cognitive disorders, prefrontal cortex, stress, aging, schizophrenia


The Arnsten lab studies the molecular regulation of the newly evolved brain circuits that subserve higher cognition, and the mechanisms that render these circuits especially vulnerable to atrophy and degeneration with advancing age, stress or disease. Our discoveries have successfully translated to treatments for cognitive disorders, including guanfacine (Intuniv) for the treatment of attention deficit hyperactivity disorder (ADHD) and emotional trauma in children, and prazosin for the treatment of post traumatic stress disorder (PTSD).