- Eugene Higgins Professor of Cell Biology, and Professor of Genetics and of Obstetrics, Gynecology, and Reproductive Sciences
- Director, Yale Stem Cell Center
Field:
Expertise:
Stem cell research, genetics
Description:
Stem cells are characterized by their ability to self-renew and to produce numerous differentiated daughter cells. These two special properties enable stem cells to play a central role in generating and maintaining most tissues in higher organisms. We study molecular mechanisms underlying the self-renewing division of stem cells. Currently, we focus on small RNA-mediated epigenetic programming and translational regulation that are required for the self-renewal of germline and embryonic stem cells. Meanwhile, we are exploring the clinical implications of our findings.
In the Media:
A new gift will spur stem cell research
Medicine @ Yale